멘토정보

멘토 정보 표 - 멘토 성명, 직급, 전공, 연구분야 안내
성명 조원경
직급 책임연구원
전공

분자생물학

연구분야 한방처방의 효능강화 연구

주요 연구실적

논문

주요 연구 실적 표-주요 연구실적에 대하여 연도, 논문명 안내
연도 논문명
2018 Anti-Inflammatory and Anti-Apoptotic Effects of Acer Palmatum Thumb. Extract, KIOM-2015EW, in a Hyperosmolar-Stress-Induced In Vitro Dry Eye Model
2017 Agastache rugosa Kuntze extract, containing the active component rosmarinic acid, prevents atherosclerosis through up-regulation of the cyclin-dependent kinase inhibitors p21WAF1/CIP1 and p27KIP1
2017 Ethanolic Extract of Melia Fructus Has Anti-influenza A Virus Activity by Affecting Viral Entry and Viral RNA Polymerase
2017 Inhibition of highly pathogenic avian influenza (HPAI) virus by a peptide derived from vFLIP through its direct destabilization of viruses
2017 Coptidis Rhizoma extract inhibits replication of respiratory syncytial virus in vitro and in vivo by inducing antiviral state
2017 Anti-inflammatory effects of Perillae Herba ethanolic extract against TNF-α/IFN-γ-stimulated human keratinocyte HaCaT cells
2017 Maydis Stigma Elicits Analgesia and Blocks Edema in Mice and Inhibits Inflammation in Macrophages
2017 Thio-barbiturate-derived compounds are novel antioxidants to prevent LPS-induced inflammation in the liver
2017 Protective Effect of Panax notoginseng Root Water Extract against Influenza A Virus Infection by Enhancing Antiviral Interferon-Mediated Immune Responses and Natural Killer Cell Activity
2017 Epimedium koreanum Nakai inhibits PMA-induced cancer cell migration and invasion by modulating NF-κB/MMP-9 signaling in monomorphic malignant human glioma cells.
2017 조골세포의 분화에 산겨릅나무 추출물이 미치는 영향
2017 조골세포의 분화에 산겨릅나무 추출물이 미치는 영향
2017 2-(3, 4-dihydroxybenzylidene)malononitrile as a novel anti-melanogenic compound
2017 Swertiajaponin inhibits skin pigmentation by dual mechanisms to suppress tyrosinase
2017 Inhibitory effects of Dianthi Herba ethanolic extract on inflammatory and nociceptive responses in murine macrophages and mouse models of abdominal writhing and ear edema
2017 Methylglyoxal and Advanced Glycation End products: Insight of the regulatory machinery affecting the myogenic program and of its modulation by natural compounds
2017 Biophysical Study on the Interaction between Eperisone Hydrochloride and Human Serum Albumin Using Spectroscopic, Calorimetric, and Molecular Docking Analyses
2017 Eupatorium fortunei and Its Components Increase Antiviral Immune Responses against RNA Viruses
2016 Anti-Inflammatory Effects of Melandrii Herba Ethanol Extract via Inhibition of NF-κB and MAPK Signaling Pathways and Induction of HO-1 in RAW 264.7 Cells and Mouse Primary Macrophages
2016 Anti-inflammatory effects of Viola yedoensis and the application of cell extraction methods for investigating bioactive constituents in macrophages
2016 Ethanol Extract of Sanguisorbae Radix Inhibits Mast Cell Degranulation and Suppresses 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis-Like Skin Lesions
2016 Herbal composition of Cinnamomum cassia, Pinus densiflora, Curcuma longa and Glycyrrhiza glabra prevents atherosclerosis by upregulating p27 (Kip1) expression
2016 Anti-Inflammatory Effect of Rhapontici Radix Ethanol Extract via Inhibition of NF-κB and MAPK and Induction of HO-1 in Macrophages
2016 Fermented Sipjeondaebo-tang Alleviates Memory Deficits and Loss of Hippocampal Neurogenesis in Scopolamine-induced Amnesia in Mice
2016 Anti-inflammatory effects of Sanguisorbae Radix water extract on the suppression of mast cell degranulation and STAT-1/Jak-2 activation in BMMCs and HaCaT keratinocytes
2016 In vitro Anti-viral Activity of Psoraleae Semen Water Extract against Influenza A Viruses
2016 Water extract of Galla Rhois with steaming process enhances apoptotic cell death in human colon cancer cells
2016 Inhibitory Effects of Viscum coloratum Extract on IgE/Antigen-Activated Mast Cells and Mast Cell-Derived Inflammatory Mediator-Activated Chondrocytes
2016 Inhibitory Effect of Loranthus parasiticus on IgE-Mediated Allergic Responses in RBL-2H3 Cells
2016 KBH-1, an herbal composition, improves hepatic steatosis and leptin resistance in high-fat diet-induced obese rats
2015 Anti-Inflammatory and Analgesic Effects of Pyeongwisan on LPS-Stimulated Murine Macrophages and Mouse Models of Acetic Acid-Induced Writhing Response and Xylene-Induced Ear Edema
2015 Antiviral Effects of Novel Herbal Medicine KIOM-C, on Diverse Viruses
2015 Epimedium koreanum Nakai Displays Broad Spectrum of Antiviral Activity in Vitro and in Vivo by Inducing Cellular Antiviral State
2015 Neuroprotective effects of Liriope platyphylla extract against hydrogen peroxide-induced cytotoxicity in human neuroblastoma SH-SY5Y cells
2015 Inhibitory Effects of Epimedium Herb on the Inflammatory Response In Vitro and In Vivo
2015 Cinnamon and its Compinents Suppress Vascular Smooth Muscle Cell Proliferation by Up-Regulation Cyclin-Dependent Kinase Inhibitors
2015 Inhibitory effect of fermented Arctium lappa fruit extract on the IgE-mediated allergic response in RBL‑2H3 cells
2015 Antioxidant and Anti-Inflammatory Activity Determination of One Hundred Kinds of Pure Chemical Compounds Using Offline and Online Screening HPLC Assay
2015 Ethanol extracts of Sanguisorba officinalis L.suppress TNF-α/IFN-γ-induced pro-inflammatory chemokine production in HaCaT cells
2014 HPLC Determination and Pharmacokinetics of Coumarin Compounds after Oral Administration of Samul-Tang to Rats
2014 Galla rhois exerts its antiplatelet effect by suppressing ERK1/2 and PLCβ phosphorylation
2014 Inhibitory effects of Palmultang on inflammatory mediator production related to suppression of NF-κB and MAPK pathways and induction of HO-1 expression in macrophages
2014 Oryeongsan inhibits LPS-induced production of inflammatory mediators via blockade of the NF-kappaB, MAPK pathways and leads to HO-1 induction in macrophage cells
2014 Isolation and Bioactivity Analysis of Ethyl Acetate Extract from Acer tegmentosum using In Vitro Assay and On-Line Screening HPLC-ABTS+ system
2014 Anti-inflammatory effect of Artemisiae annuae herba in lipopolysaccharide-stimulated RAW 264.7 Cells
2014 Screening of Bioconversion Components from Gumiganghwal-tang on Fermentation by Lactobacillus Strains
2014 Lactobacilli-Fermented Hwangryunhaedoktang has Enhanced Anti-Inflammatory Effects Mediated by the Suppression of MAPK Signaling Pathway in LPS-Stimulated RAW 264.7 Cells
2014 Guibitang, a traditional herbal medicine, induces apoptotic death in A431 cells by regulating the activities of mitogen-activated protein kinases
2013 Screening of aqueous extracts of medicinal herbs for antimicrobial activity against oral bacteria
2013 Ssanghwa-tang, an oriental herbal cocktail, exerts anti-melanogenic activity by suppression of the p38 MAPK and PKA signaling pathways in B16F10 cells
2013 Oyaksungisan, a traditional herbal formula, inhibits cell poliferation by induction of autophagy via JNK activation in human colon cancer cells
2013 Immunomodulaton and attenuation of lethal Influenza A virus infection by oral administration with KIOM-C
2013 Antithrombotic and antiplatelet activities of Soshiho-tang extract
2013 The anti-osteoporotic effect of Yijung-tang in an ovariectomized rat model mediated by inhibition of osteoclast differentiation
2013 Anti-inflammatory effect of Sosihotang via inhibition of nuclear factor-κB and mitogen-activated protein kinases signaling pathways in lipopolysaccharide-stimulated RAW 264.7 macrophage cells
2012 Anti-inflammatory effect of Lycium Fruit water extract in lipopolysaccharide-stimulated RAW 264.7 macrophage cells
2012 Fermentation by Lactobacillus Enhances Anti-Inflammatory Effect of Oyaksungisan on LPS-stimulated RAW 264.7 Mouse Macrophage Cells
2012 Effectiveness of the novel herbal medicine, KIOM-MA, and its bioconversion product, KIOM-MA128, on the treatment of atopic dermatitis
2012 ICR 마우스를 이용한 이중탕 및 발효이중탕의 급성독성 연구
2012 Fermentation improves anti-inflammatory effect of Sipjeondaebotang on LPS-stimulated RAW 264.7 cells
2012 Epimedium Koreanum Nakai water extract exhibits antiviral activity against porcine epidermic diarrhea virus in vitro and in vivo
2012 Effects of berberine and Hwangryunhaedok-Tang on oral bioavailability and pharmacokinetics of ciprofloxacin in rats
2012 Aristolochia Manshuriensis Kom inhibits adipocyte differentiation by regulation of ERK1/2 and Akt pathway
2012 In Vitro and In Vivo Genotoxicity Assessment of Aristolochia manshuriensis Kom.
2012 A Novel Herbal Medicine KIOM-MA Exerts Anti-Inflammatory Effect in LPS-Stimulated RAW 264.7 Macrophage Cells
2012 In Vitro and In Vivo Genotoxicity Assessment of Aristolochia
2012 HRT, Herbal Formula, Induces G2/M Cell Cycle Arrest and Apoptosis via Suppressing Akt Signaling Pathway in Human Colon Cancer Cells
2012 Food- and gender-dependent pharmacokinetics of paeoniflorin after oral administration with Samul-tang in rats
2011 Decursin and decursinol angelate from Angelica gigas Nakai induce apoptosis via induction of TRAIL expression on cervical cancer cells
2011 Anti-inflammatory effect of citrus unshiu peel in LPS-stimulated RAW 264.7 macrophage cells
2011 과산화수소로 유도된 산화성 간세포 손상에 대한 소시호탕(小柴胡湯)의 효과
2011 ICR 마우스를 이용한 삼소음 및 발효삼소음의 급성독성 연구
2011 인삼패독산 및 발효인삼패독산의 급성독성 연구

특허

주요 연구 실적 표-주요 연구실적에 대하여 연도, 발명의명칭, 비고 안내
연도 발명의명칭
2016 복합 생약 추출물을 유효성분으로 함유하는 항바이러스용 조성물(엔테로바이러스 71형)
2016 복합 생약 추출물을 유효성분으로 함유하는 항바이러스용 조성물(뉴캐슬병 바이러스)
2016 각막질환 또는 결막질환의 치료용 조성물
2016 복합 생약 추출물을 유효성분으로 함유하는 항바이러스용 조성물(수포성,구내염 바이러스)
2015 신곡 추출물을 포함하는 상처 치료용 조성물
2015 팔각회향 추출물 또는 이의 분획물을 포함하는 암 전이 억제용 조성물
2015 고량강 추출물을 포함하는 골 관련 질환 또는 혈관 석회화의 예방 또는 치료용 약학적 조성물
2015 길경 추출물 또는 이의 분획물을 함유하는 혈전성 질환의 예방 또는 치료용 조성물
2014 혈전증의 예방 또는 치료용 약학적 조성물 및 건강기능식품 조성물
2014 황련해독탕 및 이의 발효 조성물의 암전이 억제 활성
2014 동맥경화증 예방 또는 치료용 약학적 조성물
2014 귀비탕 유산균 발효물 및 이의 용도
2014 오약순기산 유산균 발효물 및 이의 용도
2014 산천목 추출물을 유효성분으로 함유하는 골질환의 예방 또는 치료용 약학적 조성물 및 건강기능식품
2014 관중 추출물을 유효성분으로 함유하는 골질환의 예방 또는 치료용 약학적 조성물 및 건강기능식품
2014 소시호탕의 유산균 발효물을 유효성분으로 함유하는 혈관재협착의 예방 또는 치료용 약학적 조성물 및 건강기능식품
2014 발효 보중익기탕의 뇌신경세포 보호 활성 및 인지 능력 개선 효과
2014 황련해독탕의 유산균 발효물을 유효성분으로 함유하는 골질환의 예방 또는 치료용 약학적 조성물 및 건강기능식품
2014 뇌 신경 세포 보호 활성을 갖는 십전대보탕의 유산균 발효물 및 이의 용도