멘토정보

멘토 정보 표 - 멘토 성명, 직급, 전공, 연구분야 안내
성명 서창섭
직급 선임연구원
전공 천연물화학
연구분야 한약재 및 한약 처방의 성분 분석

주요 연구실적

논문

주요 연구 실적 표-주요 연구실적에 대하여 연도, 논문명 안내
연도 논문명
2016 Simultaneous Determination of the Five Marker Compounds in Melandrium firmum using High-Performance Liquid Chromatography with Photodiode-Array Detection
2016 Traditional herbal formulas to as treatments for musculoskeletal disorders: Their inhibitory effects on the activities of human microsomal cytochrome p450s and udp-glucuronosyltransferases
2016 Inhibitory Effect of Yongdamsagan-Tang Water Extract, a Traditional Herbal Formula, on Testosterone-Induced Benign Prostatic Hyperplasia in Rats
2016 Acute and subacute toxicity of an ethanolic extract of Melandrii Herba in Crl:CD sprague dawley rats and cytotoxicity of the extract in vitro
2016 Ma Huang Tang Suppresses the Production and Expression of Inflammatory Chemokines via Downregulating STAT1 Phosphorylation in HaCaT Keratinocytes
2016 Gyeji-tang water extract exerts anti-inflammatory activity through inhibition of ERK and NF-κB pathways in lipopolysaccharide-stimulated RAW 264.7 cells
2016 Elsholtzia ciliata (Thunb.) Hylander attenuates renal inflammation and interstitial fibrosis via regulation of TGF-ßand Smad3 expression on unilateral ureteral obstruction rat model
2016 meso-Dihydroguaiaretic acid attenuates airway inflammation and mucus hypersecretion in an ovalbumin-induced murine model of asthma
2016 Quantitative Analysis and In vitro Anti‑inflammatory Effects of Gallic Acid, Ellagic Acid, and Quercetin from Radix Sanguisorbae
2016 Vascular Protective Role of Samul-Tang in HUVECs: Involvement of Nrf2/HO-1 and NO
2016 Evaluation of Anti-Inflammatory Potential of the New Ganghwaljetongyeum on Adjuvant-Induced Inflammatory Arthritis in Rats
2016 Chondroprotective and anti-inflammatory effects of ChondroT, a new complex herbal medication
2016 Protective Effects of Manassantin A against Ethanol-Induced Gastric Injury in Rats
2016 Anti-inflammatory effect and action mechanisms of traditional herbal formula Gamisoyo-san in RAW 264.7 macrophages
2016 Expression of cytochrome P450s in the liver of rats administered with socheongryong-tang, a traditional herbal formula
2016 Anti-inflammatory and antioxidant activity of the traditional herbal formula Gwakhyangjeonggi-san via enhancement of heme oxygenase-1 expression in RAW264.7 macrophages
2016 Phytochemical Analysis on Quantification and the Inhibitory Effects on Inflammatory Responses from the Fruit of Xanthii fructus
2015 Evaluation of a water extract of So-Cheong-Ryong-Tang for acute toxicity and genotoxicity using in vitro and in vivo tests
2015 Safety assessment of Guibi-Tang: subchronic toxicity study in Crl:CD SD rats
2015 Genotoxicity evaluation of Oryeong-san water extract using in vitro and in vivo tests
2015 Chungsimyeonja-eum inhibits inflammatory responses in RAW 264.7 macrophages and HaCaT keratinocytes
2015 HPLC–PDA Method for Simultaneous Determination of Nine Marker Components in Banhasasim-Tang
2015 Anti-allergic effects of sesquiterpene lactones from the root of Aucklandia lappa Decne
2015 Quality Assessment of Ojeok-San, a Traditional Herbal Formula, Using High-Performance Liquid Chromatography Combined with Chemometric Analysis
2015 Traditional Korean Herbal Formula Samsoeum Attenuates Adipogenesis by Regulating the Phosphorylation of ERK1/2 in 3T3-L1 Cells
2015 Anti-adipogenic and antioxidant effects of the traditional Korean herbal formula Samchulgeonbi-tang: an in vitro study
2015 Chrysanthemum indicum Attenuates Cisplatin-induced Nephrotoxicity both in vivo and in vitro
2015 Simultaneous determination of nine marker compounds in the traditional Korean medicine, Dangguisu‑san by high‑performance liquid chromatography
2015 Simultaneous determination of three sesquiterpene lactones in Aucklandia lappa Decne by high‑performance liquid chromatography
2015 Quantitative analysis and anti‑inflammatory effects of Gleditsia sinensis thorns in RAW 264.7 macrophages and HaCaT keratinocytes
2015 Traditional medicine yanggyuksanhwa-tang inhibits adipogenesis and suppresses proliferator-activated receptor-gamma expression in 3T3-L1 cells
2015 Development and Validation of a High-Performance Liquid Chromatographic Method for the Simultaneous Quantification of Marker Constituents in Cheonwangbosimdan
2015 Simultaneous quantification and antiatherosclerosis effect of the traditional Korean medicine, Hwangryunhaedok-tang
2015 Extracts of Scutellariae Radix inhibit low-density lipoprotein oxidation and the lipopolysaccharide-induced macrophage inflammatory response
2015 Traditional herbal formula banhasasim-tang exerts anti-inflammatory effects in RAW 264.7 macrophages and HaCaT keratinocytes
2015 Traditional Herbal Formula Oyaksungi-San Inhibits Adipogenesis in 3T3-L1 Adipocytes
2015 Traditional herbal formula Jakyakgamcho-tang (Paeonia lactiflora and Glycyrrhiza uralensis) impairs inflammatory chemokine production by inhibiting activation of STAT1 and NF-kappa B in HaCaT cells
2015 Anti-inflammatory Actions of Herbal Formula Gyejibokryeong-Hwan Regulated by Inhibiting Chemokine Production and STAT1 Activation in HaCaT Cells
2014 Antioxidant and Antiadipogenic Activities of Galkeun-Tang, a Traditional Korean Herbal Formula
2014 Subacute Oral Toxicity of Yukmijiwhang-Tang in Crl:CD Sprague-Dawley Rats and Its Cytotoxicity
2014 Trichosanthes kirilowii ameliorates cisplatin-induced nephrotoxicity in both in vitro and in vivo
2014 Inhibitory activity of Socheongryong-tang and its constituent components against the production of RANTES, eotaxin, eotaxin-3, and MMP-9 from BEAS2B-cells
2014 Optimization of the extraction process for the seven bioactive compounds in Yukmijihwang‑tang, a herbal formula, using response surface methodology
2014 Chemical interaction between Paeonia lactiflora and Glycyrrhiza uralensis, the components of Jakyakgamcho-tang, using a validated HPLC method
2014 HPLC-PDA Simultaneous Determination and Protective Effect of Anemarrhena asphodeloides Against Acute Renal Failure
2014 Simultaneous determination of liquiritin, nodakenin and glycyrrhizinin Guibi-tang, a traditional herbal prescription by HPLC-PDA
2014 α-Spinasterol from Melandrium firmum attenuates benign prostatic hyperplasia in a rat model.
2014 Non-clinical safety assessment of Hwangryunhaedok-tang: 13-week toxicity in Crl:CD Sprague Dawley rats
2014 Development of a quantitative analysis method for the 12 marker compounds in Palmijihwang-hwan, a herbal formula, using a reversed-phase C18 column and an amino column by HPLC
2014 Genotoxicity evaluation of Guibi-Tang extract using an in vitro bacterial reverse mutation assay, chromosome aberration assay, and in vivo micronucleus test
2014 Development of validated determination of the eleven marker compounds in Gyejibokryeong-hwan for the quality assessment using HPLC analysis
2014 Safety assessment of So-cheong-ryong-tang: subchronic toxicity study in Crl:CD Sprague Dawley rats.
2014 Simultaneous Determination of 13 Chemical Marker Compounds in Gwakhyangjeonggi-san, a Herbal Formula, with Validated Analytical Methods
2014 Antiatopic Dermatitis Effect of Artemisia iwayomogi in Dust Mice Extract-Sensitized Nc/Nga Mice
2014 Artemisia capillaris inhibits atopic dermatitis-like skin lesions in Dermatophagoides farinae-sensitized Nc/Nga mice
2014 Simultaneous quantification and inhibitory effect on LDL oxidation of the traditional Korean medicine, Leejung-tang
2014 Simultaneous determination of ten constituents in herbal formulation Sipjeondaebo-tang using HPLC-PDA
2014 Effect of sauchinone, a lignan from Saururus chinensis, on bacterial phagocytosis by macrophages
2014 Evaluation of the genotoxicity of bangpungtongsung-san, a traditional herbal prescription
2013 Compositional differences of Bojungikgi-tang decoctions using pressurized or non-pressurized extraction methods with variable extraction times
2013 Sauchinone, a lignan from Saururus chinensis, attenuates neutrophil pro-inflammatory activity and acute lung injury
2013 Simultaneous Determination of Gallic Acid, Ellagic Acid, and Eugenol in Syzygium aromaticum and Verification of Chemical Antagonistic Effect by the Combination with Curcuma aromatica Using Regression Analysis
2013 장기보존시험에 따른 보중익기탕 전탕팩의 유통기한 평가
2013 Determination of 5-hydroxymethyl-2-furfural, albiflorin, paeoniflorin, liquiritin, ferulic acid, nodakenin, and glycyrrhizin by HPLC-PDA, and evaluation of the cytotoxicity of Palmul-tang, a traditional Korean herbal medicine
2012 장기보존시험에 따른 쌍화탕의 유통기한 설정
2012 Simultaneous Determination of Seven Constituents in Herbal Prescription Jaeumganghwa-tang Using HPLC-PDA

특허

주요 연구 실적 표-주요 연구실적에 대하여 연도, 발명의 명칭 안내
연도 발명의 명칭
2016 지실 추출물을 포함하는 전립선 관련 질환의 예방 또는 치료용 조성물
2014 천연물 추출물을 유효성분으로 함유하는 급성신부전의 예방 또는 치료용 약학적 조성물
2014 천연물 추출물 또는 이의 분획물을 유효성분으로 함유하는 급성신부전의 예방 또는 치료용 약학적 조성물
2014 지실 추출물을 포함하는 전립선 관련 질환의 예방 또는 치료용 조성물
2013 천연물 추출물을 유효성분으로 함유하는 급성신부전의 예방 또는 치료용 약학적 조성물
2013 천연물 추출물 또는 이의 분획물을 유효성분으로 함유하는 급성신부전의 예방 또는 치료용 약학적 조성물